国际眼科杂志2016，Vol.16Issue(12)：2247-2249,3.DOI:10.3980/j.issn.1672-5123.2016.12.19
羧甲基纤维素钠眼液联合rhEGF治疗白内障术后干眼症
Clinical study of carboxymethylcellulose sodium eye drops and rhEGF in treating dry eye after cataract surgery
黄德磊 1刘英豪 1傅宏 1段惠静 1林柏松1
作者信息
- 1. 163453 中国黑龙江省大庆市，大庆龙南医院眼科
- 折叠
摘要
Abstract
• AIM: To explore the clinical effect of carboxymethylcellulose sodium eye drops and recombined human epidermal growth factor ( rhEGF ) on the cataract patients with dry eye after phacoemulsification.•METHODS: A total of 150 patients with cataract ( 150 eyes) referred to our hospital from Oct. 2015 to May 2016 were randomly divided into trial group and control group, 75 cases in each group. All patients after cataract phacoemulsification were received the treatment of dry eye according to different groups. In treatment goup, patients were treated by carboxymethylcellulose sodium eye drops and rhEGF. In control group, patients were treated by carboxymethylcellulose sodium eye drops. The subjective dry eye symptoms, as well as fluorescein staining ( FL) , Schirmer ▏ test ( S▏t) and tear break-up time ( BUT) were recorded before treatment, 1wk, 1mo after treatment.•RESULTS: Before treatment, there were no significant differences between groups in the subjective dry eye symptoms and the results of BUT, FL and S▏t (P>0. 05). After treatment, all the index in two groups significantly improved over time (P<0. 01), and all the index were better in treatment group than those in control group ( P<0. 05). The treatment group had less severe subjective dry eye symptoms, longer BUT, fewer FL, and more S▏t.•CONCLUSION:Combined use of carboxymethylcellulose sodium eye drops and rhEGF can relieve the dry eye <br> symptoms and maintain the tear film stable after phacoemulsification effectively. Therapeutic effects of combined utilization are better than that of carboxymethylcellulose sodium eye drops used alone.关键词
白内障超声乳化术/干眼症/羧甲基纤维素钠眼液/重组人表皮生长因子Key words
phacoemulsification cataract surgery/dry eye symptoms/carboxymethylcellulose sodium eye drops/recombined human epidermal growth factor引用本文复制引用
黄德磊,刘英豪,傅宏,段惠静,林柏松..羧甲基纤维素钠眼液联合rhEGF治疗白内障术后干眼症[J].国际眼科杂志,2016,16(12):2247-2249,3.
