陕西中医2016,Vol.37Issue(12):1600-1602,3.DOI:10.3969/j.issn.1000-7369.2016.12.014
膝骨关节炎采用独活寄生汤辅助效果及对关节滑液中细胞因子的影响
Knee osteoarthritis patients with Duhuo Jisheng adjuvant treatment and its effecton patients with synovial fluid cytokine
摘要
Abstract
Objective:To investigate the clinical efficacy of knee osteoarthritis Duhuo Jisheng adjuvant treat-ment .Methods :A retrospective analysis of 86 patients with knee osteoarthritis clinical patient records and treatment ,in which the continuous intra-articular injections of sodium hyaluronate were three times as the control group ,43 cases ;the other 43 cases in the control group on the basis of Duhuo Jisheng treatment the observation group .Before and after using visual analogue scale (VAS) evaluation of joint pain cases ,the use of the former KSS score evaluable patients after treat-ment of knee function were detected before and after treatment in the synovial fluid of nitric oxide (NO) and superoxide dismutase enzyme (SOD) content ,statistical clinical efficacy and adverse reactions .Results :After treatment ,both groups VAS score and knee scores were significantly improved indicators ,then the degree of improvement in observation group than the control group significantly .Two groups of patients after treatment significantly increased SOD levels than before treatment ,NO levels were significantly decline ,and then the observation group SOD level and increased levels of NO lev-el decreased significantly better than the control group .Observation group total effective rate was 95 .3% ,significantly higher than 76 .7% .Only two minor adverse events during treatment ,follow-up treatment and did not affect the results . Conclusion :Applications Duhuojisheng adjuvant treatment of knee osteoarthritis significantly and safe .关键词
骨关节炎,膝/中西医结合疗法/@独活寄生汤/细胞因子类Key words
Osteoarthritis,knee/Integrated/Chinese traditional and western medicine therapy/@Duhuo Jisheng Cytokines分类
医药卫生引用本文复制引用
王雷,闫相斌..膝骨关节炎采用独活寄生汤辅助效果及对关节滑液中细胞因子的影响[J].陕西中医,2016,37(12):1600-1602,3.基金项目
陕西省卫生和计划生育委员会项目(20160322 ) (20160322 )