陕西中医2016，Vol.37Issue(12)：1688-1691,4.DOI:10.3969/j.issn.1000-7369.2016.12.054
四君子汤总多糖对小鼠肠道菌群及免疫功能的影响
Effect of total polysaccharides of Sijunzi decoction on intestinal floraand immune function in mice
摘要
Abstract
Objective:To discuss the effect of total polysaccharides of Sijunzi decoction on intestinal flora and immune function in mice .Methods:100 healthy mice were divided into 4 groups ,each of 25 cases .Mice of high dose group ,low dose group and model control group were spleen deficiency modelled .Normal control group and model control group were filled with normal saline every day ,and low dose group was filled with Sijunzi decoction 1g/kg ,and the high dose group was filled with Sijunzi decoction 2g/kg .The effect of total polysaccharides of Sijunzi decoction on intestinal flora and immune function in mice was analyzed .Results :Thymus index and the Peyer's patch of the low dose group and high dose group were higher than the model control group ,and the difference was statistically significant .Intestinal sIgA content were higher than the model control group ,and the difference was statistically significant .T lymphocyte ratio of the low dose group was higher than the model control group .Bacillus ,bacillus ,lactobacillus ,escherichia coli ,bacillus sp levels of the model control group were higher than the normal control group ,and those of the high dose group were lower than the model control group .Conclusion :Sijunzi decoction can correct the intestinal flora imbalance ,restore the immune function of spleen deficiency mice ,and there is a dose dependent .关键词
胃肠道/自身免疫/四君子汤Key words
Castrointestinal/tract Autoimmunity/@Sijunzi decoction分类
医药卫生引用本文复制引用
唐华羽,李玉芝,李长德,解云川..四君子汤总多糖对小鼠肠道菌群及免疫功能的影响[J].陕西中医,2016,37(12):1688-1691,4.基金项目
黑龙江省卫生计生委科研课题(2014-237 ) （2014-237 ）
