中国感染控制杂志2016,Vol.15Issue(11):817-820,4.DOI:10.3969/j.issn.1671-9638.2016.11.003
深圳市儿童医院儿童粪便分离的459株沙门菌分布特征及耐药性
Distribution characteristics and antimicrobial resistance of 459 strains of Salmonella isolated from feces of children in Shenzhen Children’s Hospi-tal
摘要
Abstract
Objective To understand the distribution characteristics and antimicrobial resistance of Salmonella isolated from feces of children.Methods Salmonella were isolated from fecal specimens of children in a hospital be-tween January 2012 and October 2015,serotypes and susceptibility of Salmonella to commonly used antimicrobial agents were analyzed.Results A total of 7 047 children’s fecal specimens were detected,459 (6.51%)children were isolated Salmonella,the ratio of male to female was 2.4 ∶1,352 (76.69%)children were less than 3 years old;374 strains (81.48%)were isolated from May to October,the numbers of stains isolated in July,August,and September were 72,84,and 78 respectively.Salmonella group B and group D were the most common serotypes,accounting for 69.06%and 19.39% respectively,most were serotypes of Salmonella typhimurium (S.typhimurium)and Salmonella enteritidis (S.enteritidis).No imipenem-or ertapenem-resistant strains were found,susceptibility of Salmonella to piperacillin/tazobactam,cefepime,ceftazidime,aztreonam,and ceftriaxone were all >70%,susceptibility rate of S.enteritidis to cephalosporins was lower than S.typhimurium,but to compound sulfamethoxazole was higher than S.typhimurium. Conclusion Salmonella are mainly isolated from children less than 3 years old in this hospital,summer and autumn are peak seasons,the main serotypes were S.typhimurium and S.enteritidis,antimicrobial therapy should be carefully select-ed in combination with serotypes and antimicrobial susceptibility testing result.关键词
沙门菌/血清型/儿童/粪便/抗药性,微生物/耐药性/流行病学特征Key words
Salmonella/serotype/child/feces/drug resistance,microbial/drug resistance/epidemiological characteristic分类
医药卫生引用本文复制引用
王红梅,王和平,雷旻,周高枫,张交生,彭宝玲,张锐沐,邓继岿..深圳市儿童医院儿童粪便分离的459株沙门菌分布特征及耐药性[J].中国感染控制杂志,2016,15(11):817-820,4.基金项目
深圳市科技研发资金(JCYJ20160429175723608);深圳市儿童医院重点专科资助项目 ()