摘要
Abstract
Objective To explore the clinical effect of the treatment of early diabetic nephropathy patients with the combination of sodium.Methods From May 2012 to August 2015,126 cases of early to visit Liaoning Provincial People's Hospital of type 2 diabetic nephropathy patients as the research object,randomly divided into observation group(66 cases) and control group(60 cases).Al patients were given 2 weeks of diabetes education and basic treatment of diabetes.On this basis,the control group of patients with oral Valsartan Capsules,the observation group in the control group based on the treatment of patients with oral Beraprost Sodium Tablets, are continuing treatment for 16 weeks.Comparison of two groups of patients with therapeutic effect;two groups of patients with serum cystatin C (CysC) levels compared with before treatment a downward trend, but the difference was not statisticaly significant (P>0.05),and serum creatinine (SCr) and urea nitrogen (BUN) levels showed no significant difference(P>0.05),and two groups of patients had no adverse reactions clear.Results After treatment,observation group of patients with urinary albumin(ALB),urinary albumin excretion rate (UAER) and urinary albumin/creatinine ratio (ACR) levels were significantly lower than the control group,the differences were statisticaly significant(P<0.05).Conclusion Sodium combined with valsartan can effectively reduce the level of ALB in patients with early diabetic nephropathy, and improve renal function.关键词
糖尿病肾病/贝前列素钠/缬沙坦/尿微量清蛋白Key words
Diabetic nephropathy/Beraprost sodium/Valsartan/Urine specimen album分类
医药卫生
