磁共振成像2016，Vol.7Issue(11)：804-807,4.DOI:10.12015/issn.1674-8034.2016.11.002
扩散峰度成像在正常成人脑组织中可重复性的研究
The repeatability of diffusion kurtosis imaging on the brain tissue in healthy adults
摘要
Abstract
AbstractObjective:To study the reproducibility of diffusion kurtosis imaging (DKI) on the brain tissue in healthy adults.Materials and Methods:Twenty-six healthy volunteers aged from 31 to 66 years were enrolled into this present study. All enrolled subjects were scanned with the DKI sequence on their head and b-factors of 0, 500, 1000, 1500, and 2000 s/mm2 were applied. Two observers (experienced radiologist) independently interpreted the acquired DKI images and conducted the measurement of diffusion coefficient (MD) and diffusion kurtosis coefficient (MK). All statistical analysis were conducted on the SPSS 19.0 software, and the inter-and intra-observer consistency of diffusion coefficient (MD) and diffusion kurtosis coefficient (MK) were tested by the repeatability measurements.Results:The MD and MK of the genu and splenium of the corpus callosum, the anterior and posterior limbs of internal capsule and thalamus were measured by two observers at the different time-points respectively. As a result, the difference between the measurements conducted by the same observer at the different times (intra-observer) was not statistically signiifcant (P>0.05), whereas the difference between the measurements between different observers (inter-observer) was also not statistically signiifcant (P>0.05).Conclusions:The parameter measurements of DKI on the brain tissues of normal adults are repeatable and may be potentially used to relfect the changes of the micro-structures of brain tissue.关键词
扩散峰度成像/扩散系数/扩散峰度系数/可重复性测定Key words
Diffusion kurtosis imaging/Diffusion coefficient/Diffusion kurtosis coefifcient/Repeatability分类
医药卫生引用本文复制引用
鲍道亮,张梅芳,苏丽清,肖友平,曹喜生,姚逸琦,陈韵彬..扩散峰度成像在正常成人脑组织中可重复性的研究[J].磁共振成像,2016,7(11):804-807,4.基金项目
福建省科技厅社会发展引导性重点基金项目、国家临床重点专科建设项目和福建省临床重点专科建设项目(编号2014Y0013) （编号2014Y0013）
