动物医学进展2016,Vol.37Issue(11):97-101,5.
鸡心包积水综合征疫苗研究进展
Progress on Hydropericardium Syndrome Vaccine
程小果 1王慧 1程宁 2陈申秒 1朱杰 1宿春虎 1郭建友 1张小荣 3吴艳涛3
作者信息
- 1. 山东滨州沃华生物工程有限公司,山东滨州 256606
- 2. 山东畜牧兽医专科学校,山东潍坊 261061
- 3. 扬州大学兽医学院,江苏扬州 225009
- 折叠
摘要
Abstract
Hydropericardium syndrome(HPS)is a newly occurred chicken disease caused by Fowl adenovi-rus serotype-4(FAdV-4).The disease has caused huge economic losses to the poultry industry since it′s fast spread and high mortality rate.HPS was reported first time in 1987 at Angara goth,a broiler produ-cing area near Karachi Metropolitan city of Pakistan.It was firstly reported in China in 2013,and then spread widely in Henan,Shandong,Jiangsu and other provinces.Besides vaccination,there were no effec-tive therapies for this disease.Formalinized aqua based liver organ vaccines for HPS were effective for the control of the disease in Pakistan and other epidemic countries and regions,which has obvious deficiencies such as unstable efficiency and greater risk of secondary infection.Inactivated FAdV-4 virus vaccines were safe and stable but the costs were much higher.In addition,live vaccines also have provided quite effective protection while the drawbacks were virulence return.Recombinant protein vaccines take a good develop-ment and application prospects in the future since their safety and efficiency.The progress on the study of HPS vaccines was summarized in this paper in order to find the proper vaccines and methods for controlling HPS in the future.关键词
心包积水综合征/禽腺病毒C种血清4型/安卡拉病/疫苗Key words
Hydropericardium syndrome/FAdV-4/angara disease/vaccine分类
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程小果,王慧,程宁,陈申秒,朱杰,宿春虎,郭建友,张小荣,吴艳涛..鸡心包积水综合征疫苗研究进展[J].动物医学进展,2016,37(11):97-101,5.