湖南中医药大学学报2016，Vol.36Issue(11)：64-67,4.DOI:10.3969/j.issn.1674-070X.2016.11.017
健脾解毒方联合化疗治疗大肠癌术后患者的临床观察
Clinical Observation of Jianpi Jiedu Fang Combined with Chemotherapy on the Treatment of Postoperative Patients with Colorectal Cancer
摘要
Abstract
Objective To observe the clinical efficacy of Jianpi Jiedu Fang (JPJDF) combined with chemotherapy on the treatment of patients with stage II-III colorectal cancer after operation and its effects on immune function. Methods The 40 cases of colorectal cancer were divided into two groups, treatment group and control group, 20 cases in each group. Patients of two groups were treated with FOLFOX4 chemotherapy, but the treatment group was given JPJDF (one dose every day, continuously for 8 weeks). Every 2 weeks repeated 1 times, 1 times for 1 cycles, the clinical efficacy and immune function in the two groups were observed after 4 cycles. Results After the end of observation, the total efficiency of the treatment group was higher than that of the control group (P<0.05); the total scores of TCM syndromes in patients of the two groups were improved after treatment, there were differences between the two groups (P<0.01). After the end of treatment, the KPS score of treatment group was better than the control group , the difference was statistically significant (P<0.05); the CD3+, CD4+, CD4+/CD8+ index value was better than the control group, the difference was significant (P<0.01). Conclusion JPJDF can increasethe clinical efficacy, improve the quality of life and enhance the immune function of patients with colorectal cancer.关键词
大肠癌/健脾解毒方/化疗/临床疗效/免疫功能Key words
colorectal cancer/Jianpi Jiedu Fang/chemotherapy/clinical efficacy/immune function分类
医药卫生引用本文复制引用
雷彩云,雷三林,张英进,张四方,毛丹,丁陈陈,施利,张绍钒,林丰夏,黄建华,刘新义,马进安..健脾解毒方联合化疗治疗大肠癌术后患者的临床观察[J].湖南中医药大学学报,2016,36(11):64-67,4.基金项目
国家自然科学基金面上项目（81273722）。 （）
