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白芷和藁本药对提取工艺研究

王娟 马春梅 袁绍莉 王丹

药学研究2016,Vol.35Issue(11):632-634,3.
药学研究2016,Vol.35Issue(11):632-634,3.DOI:10.13506/j.cnki.jpr.2016.11.003

白芷和藁本药对提取工艺研究

Extraction process of the combination of Angelica dahurica and Ligusticum sinense Oliv

王娟 1马春梅 2袁绍莉 1王丹2

作者信息

  • 1. 徐州生物工程职业技术学院,江苏 徐州 221006
  • 2. 徐州市生物制药研发工程中心,江苏 徐州 221006
  • 折叠

摘要

Abstract

Objective To optimize the extraction process of the combination of Angelica dahurica and Ligusticum sinense Oliv.Methods The preparation process was investigated by L9(34 )orthogonal design with content of imperatorin and the rate of extractum as indexes,using the determination of the content of imperatorin by HPLC.The main factors influ-encing the extraction efficiency such as the amount of added ethanol,ethanol concentration,the time of extraction and times of extraction were investigated.Results The optimum technical condition was as follows:8 times amount of 80% ethanol of soaking 1 hours,extract 3 times and 90 minutes for each time.Conclusion The optimized extraction process was simple, stable and feasible,it can be used in the preparation.

关键词

白芷-藁本药对/正交试验/提取工艺/欧前胡素

Key words

Combination of Angelica dahurica and Ligusticum sinense Oliv/Orthogonal test/Extraction process/Impera-torin

分类

医药卫生

引用本文复制引用

王娟,马春梅,袁绍莉,王丹..白芷和藁本药对提取工艺研究[J].药学研究,2016,35(11):632-634,3.

基金项目

徐州生物工程职业技术学院科技计划项目 ()

药学研究

2095-5375

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