药学研究2016，Vol.35Issue(11)：650-652,3.DOI:10.13506/j.cnki.jpr.2016.11.008
首乌益智胶囊挥发油的提取和包合工艺研究
Research of extraction and inclusion technology of volatile in Shouwuyizhi Capsules
摘要
Abstract
Objective To optimize the process of volatile oil extraction and β-cyclodextrin( β-CD)inclusion from Fructus Alpiniae Oxyphyllae and Rhizoma Chanxiong in Shouwuyizhi Capsules. Methods Amount of volatile oil was adopted as observation index,and extraction process of volatile oil was optimized by orthogonal test.Inclusion rate of volatile oil and yield of inclusion compound were used as comprehensive assessment parameters to optimize β-CD inclusion technol-ogy and perform inclution validation.Results The optimum extraction process of volatile oil were:water volume of 8 time, extraction time 5 hours;The optimum inclusion technology of volatile oil were:ratio of volatile oil to β-CD was 1: 9,inclu-sion temperature 35 ℃,inclusion time 2 hours.Conclusion The optimized extraction technology had a high rate of oil yield.The optimized inclusion technology was stable,had a high rate of inclusion.The operation method was simple,it can be used as the preparation of volatile oil extraction and inclusion process.关键词
首乌益智胶囊/挥发油/β-环糊精/包合Key words
Shouwuyizhi Capsules/Volatile oil/β-cyclodextrin/Inclusion分类
化学化工引用本文复制引用
丁晓彦,张新军,赵渤年..首乌益智胶囊挥发油的提取和包合工艺研究[J].药学研究,2016,35(11):650-652,3.基金项目
山东省自主创新及成果转化专项 （）
