世界中医药2016，Vol.11Issue(10)：2138-2140,2144,4.DOI:10.3969/j.issn.1673-7202.2016.10.055
疏血通联合硫辛酸治疗糖尿病周围神经病变的Meta分析
Meta-Analysis for Shuxuetong Combined withα-Lipoic Acid in Treatment of Diabetic Peripheral Neuropathy
摘要
Abstract
Objective:Using Meta analysis of shuxuetong combine with α-lipoic acid clinical effect on treatment of diabetic periph-eral neuropathy by systematic review .And the analysis of the results guides clinical medication options .Methods:"Diabetic neu-ropathy","α-lipoic acid" and "Shuxuetong" were adopted as the search terms for comprehensive search in databases .Meta analy-sis was applied for literature relevant to Shuxuetong combined with α-lipoic acid therapy and α-lipoic acid therapy in the treatment of diabetic peripheral neuropathy .Results:Six papers including 614 patients with diabetic peripheral neuropathy were analyzed and the valid rate of α-lipoic acid treatment group was significantly higher than that of the control group (RD=0.19,95%CI [0.13, 0.25],P<0.01).Conclusion:Shuxuetong combine with α-lipoic acid,compared with single α-lipoic acid therapy may effectively relieve the symptoms of diabetic peripheral neuropathy .As issues existed in methodology for the selection of literature ,authenticity of the results may be affected .Rigorous,large sample,multi-center,randomized,controlled clinical trial will be further designed to validate the study .关键词
α-硫辛酸/疏血通/糖尿病周围神经病变/Meta分析Key words
α-Lipoic acid/Shuxuetong/Diabetic peripheral neuropathy/Meta Analysis分类
医药卫生引用本文复制引用
孙心怡,缪鋆鋆,王丽娟,葛静..疏血通联合硫辛酸治疗糖尿病周围神经病变的Meta分析[J].世界中医药,2016,11(10):2138-2140,2144,4.基金项目
江苏省中医药局项目——2 型糖尿病下肢血管病变血清 IMA、Lp-PLA2 的表达及藤芪通络颗粒干预的作用研究 (编号:FY201506) （编号:FY201506）
