中国组织工程研究2016,Vol.20Issue(46):6986-6992,7.DOI:10.3969/j.issn.2095-4344.2016.46.020
运动性心肌顿抑:事实还是谬论?
Exercise-induced myocardial stunning:fantasy or reality?
摘要
Abstract
BACKGROUND:A series of studies have pointed out that the reversible myocardial dysfunction caused by long-term and high-intensive exercising is similar to the ventricular dysfunction fol owing myocardial stunning. OBJECTIVE:To review the research of exercise-induced myocardial stunning at home and abroad, and to provide theoretical basis and practical guidance for study on the relationship of high-intensive exercising with exercise risks. METHODS:The articles about exercise-induced myocardial stunning published from February 1964 to February 2016, were searched from PubMed and CNKI databases with the keywords of“exercise, myocardial stunning”OR“exercise-induced myocardial stunning”in English and Chinese, respectively. Final y 50 eligible literatures were enrol ed for analysis. RESULTS AND CONCLUSION:Myocardial stunning, a symptom of heart dysfunction, is closely linked with ischemia/reperfusion. The present research on the relationship between exercise and myocardial stunning mainly focuses on the protection of exercise against myocardial stunning. It has been confirmed that the myocardial stunning can be induced by exercise in patients with cardiovascular diseases, and myocardial stunning occurs in rats undergoing exhaustive treadmil running. Changes of heart structure and function caused by exercising have been extensively explored, so exercise-induced myocardial stunning should exist in healthy people. To conclude, exercise-induced myocardial stunning does exist, and is an important concept to assess the risk of strenuous exercise.关键词
组织构建/组织工程/心肌顿抑/抗氧化剂/热休克蛋白/运动性心肌顿抑分类
医药卫生引用本文复制引用
李顺昌..运动性心肌顿抑:事实还是谬论?[J].中国组织工程研究,2016,20(46):6986-6992,7.基金项目
国家体育总局科研项目(10B038);西昌学院自然科学项目(XA1205);国家留学基金资助(201405620017)@@@@the Scientific Research Project of General Administration of Sport of China, No.10B038 (10B038)
the Natural Science Foundation of Xichang University, No. XA1205 ()
the Grant from China Scholarship Council, No.201405620017 ()