现代医药卫生2016，Vol.32Issue(22)：3456-3457,3461,3.DOI:10.3969/j.issn.1009-5519.2016.22.014
NT-proBNP和cTnI在慢性心力衰竭中的诊断价值及预后评价
Diagnostic value and prognostic evaluation of NT-proBNP and cTn I in chronic heart failure
张海云 1左顺英1
作者信息
- 1. 平顶山煤业集团一矿医院心血管内科，河南平顶山467000
- 折叠
摘要
Abstract
Objective To investigate the diagnostic value and prognostic evaluation of NT-proBNP and cTn I level change in chronic heart failure(CFH). Methods One hundred and ten cases of CHF(cardiac function gradeⅠ~Ⅳ)in our hospi-tal from January 2014 to May 2016 were selected as the patients group and contemporaneous 50 individuals undergoing physical examination were selected as the control group. The electrochemiluminescence and enzyme-linked immunosorbent assay(ELISA) were adopted to respectively detect NT-proBNP and cTn I levels in the two groups. Then the comparative analysis was conducted. Results The NT-proBNP and cTnI levels in the patients group were(1 781.74±268.36)ng/mL and (0.57±0.08)ng/mL respectively, which were significantly higher than (81.29±24.25) and (0.05±0.01)ng/mL,the differences were statistically significant(P<0.05). The NT-proBNP and cTnI levels in the patients group were increased with the cardiac function decrease;the NT-proBNP and cTn I levels in the gradeⅡ~Ⅳgroup were significantly higher than those in the gradeⅠgroup,the difference was statistically signifi-cant(P<0.05). Conclusion The NT-proBNP and cTn I level change is positively correlated with the disease aggravation degree in CHF patients. Their combined detection can provide a basis for the diagnosis and severity evaluation of CFH patients.关键词
肌钙蛋白I/慢性病/心力衰竭/诊断/N-端脑钠肽前体Key words
Troponin I/Chronic disease/Heart failure/diagnosis/N-terminal brain natriuretic peptide引用本文复制引用
张海云,左顺英..NT-proBNP和cTnI在慢性心力衰竭中的诊断价值及预后评价[J].现代医药卫生,2016,32(22):3456-3457,3461,3.
