厦门大学学报（自然科学版）2016，Vol.55Issue(6)：781-792,12.DOI:10.6043/j.issn.0438-0479.201604104
拟南芥茎尖干细胞调控机制的研究进展
Research Progresses of the Regulatory Mechanism of the Shoot Apical Stem Cell in Arabidopsis
摘要
Abstract
The shoot apical stem cell is a pool of pluripotent cell in the apex of the plant,which is the source of the whole parts above the ground.The stem cell divides to produce two daughter cells.One can renew itself,and the other can form the organ promordia for proliferation.At last the stem cell stablizes in homeostasis,which can maintain plant development even up to a thousand years. Modern molecular biology and genetics have indicated that the homeostasis is regulated exactly by various factors from stem cell niche.The key pathway among the network is the negative feedback loop between the WUSCHEL (WUS)gene and the CLAVATA (CLV)gene.Other biological factors,such as cytokinin,the moved small RNAs and the epigenetics effects,play a role on this loop eventually.Besides,the SHOOTMERISTEMLESS (STM)signaling pathway,which is parallel to the WUS-CLV loop,plays a posi-tive role in stem cell maintenance.This article mainly reviewed the latest research progresses on the molecular mechanism of stem cell maintenance in model plant Arabidopsis.关键词
茎尖干细胞/WUS-CLV/细胞分裂素/小RNAs/表观遗传/STMKey words
stem cell maintenance/WUS-CLV/cytokinin/small RNAs/epigenetics/STM分类
生物科学引用本文复制引用
崔玉超,陈亮..拟南芥茎尖干细胞调控机制的研究进展[J].厦门大学学报（自然科学版）,2016,55(6):781-792,12.基金项目
国家重点研发计划项目(2016YFD0100903) （2016YFD0100903）
国家自然科学基金(31560297) （31560297）
