中国全科医学2016，Vol.19Issue(35)：4316-4322,7.DOI:10.3969/j.issn.1007-9572.2016.35.006
心肺运动试验精准制定个体化适度强度运动康复处方治疗高血压的疗效研究
Effects of CPET - based Precise Formulation of Individualized Moderate - intensity Exercise Prescription on Hypertension
摘要
Abstract
Objective Cardiopulmonary exercise testing(CPET)was used to evaluate the overall function objectively and quantitatively in this study,and based on the results,an individualized moderate intensity exercise prescription was formulated precisely. The aim of this study was to investigate the effects of individualized moderate - intensity exercise prescription with holistic rehabilitation protocols on hypertension. Methods From Beijing Rehabilitation Hospital of Capital Medical University,we recruited 5 medical workers with confirmed hypertension and administration of anti - hypertensive drugs to perform symptom - limited extreme CPET. According to the data of CPET,an individualized moderate - intensity exercise training protocol with watts between anaerobic threshold and peak was designed,and patients were treated with the overall rehabilitation program including the optimization of drugs,mental and psychological management,living habits,smoking and alcohol restrictions. Blood pressure was continuously monitored during exercise training. Resting blood pressure was measured before and after exercise, respectively. Patients did daily exercise training for 12 weeks,and medication was adjusted according to the stable level of blood pressure during the training period. Results Patients with hypertension were treated with at least one antihypertensive drug before exercise,then they gradually stopped taking antihypertensive drugs after exercise therapy,and all of them did not take any antihypertensive drugs by the twelfth weeks of exercise therapy. Compared with before exercise training,the SBP of the patients after exercise training was much lower〔(116 ± 10)mm Hg vs. (125 ± 11)mm Hg,1 mm Hg = 0. 133 kPa,P < 0. 05〕,and so was the DBP〔(71 ± 7)mm Hg vs.(74 ± 8)mm Hg,P < 0. 05〕. The resting SBP of the patients before exercise training at the twelfth weeks of exercise therapy was significantly lower than that at the first week(P < 0. 05). There was no significant difference in the resting SBP of the patients after exercise training between the first and twelfth weeks of exercise therapy(P >0. 05). The resting DBP of the patients before or after exercise training demonstrated no statistically significant difference between the first and twelfth weeks of exercise therapy(P > 0. 05). Conclusion For patients with hypertension,holistic rehabilitation protocols centered on individualized moderate - intensity exercise prescription precisely designed on the basis of overall function evaluated by CPET objectively and quantitatively,can obtain an amazing effect of decreasing the blood pressure,and the blood pressure still remains stable after stopping taking drugs. It is worth doing an advanced study among more patients in the future.关键词
高血压/心肺运动试验/康复/治疗结果Key words
Hypertension/Cardiopulmonary exercise testing/Rehabilitation/Treatment outcome分类
医药卫生引用本文复制引用
葛万刚,孙兴国,刘艳玲,冯静,席家宁,张振英..心肺运动试验精准制定个体化适度强度运动康复处方治疗高血压的疗效研究[J].中国全科医学,2016,19(35):4316-4322,7.基金项目
国家高技术研究发展计划（863计划）课题（2012AA021009）；国家自然科学基金医学科学部面上项目（81470204）；中国医学科学院国家心血管病中心阜外医院科研开发启动基金（2012- YJR02）；首都临床特色应用研究（Z141107002514084）；首都临床特色应用研究与成果推广 （）
