中国全科医学2016，Vol.19Issue(35)：4370-4374,5.DOI:10.3969/j.issn.1007-9572.2016.35.016
浙江省象山县结节性甲状腺肿检出率及影响因素调查研究
Investigation in Eetection Rate and Influencing Factors of Nodular Goiter in Xiangshan County of Zhejiang Province
摘要
Abstract
Objective To investigate the detection rate of nodular goiter and the influencing factors for nodular goiter in Xiangshan county. Methods Used the multi - stage cluster random sampling in 2013,5 towns were sampled from 17 towns in Xiangshan county;2 villages were sampled from those 5 towns respectively,hence 10 villages were sampled in total. The population was divided by topographical features into 4 groups:town group,mountain group,plain group and island group. Residents older than 18 years old and resided in Xiangshan county longer than 6 months were enrolled in this study. The people included were examined if they suffered from thyroid nodules by color Doppler ultrasonography. The patients diagnosed with nodular goiter were arranged into case group;the same amount of people without nodular goiter diagnosed by B-ultrasonography in the same townships and villages were arranged into control group;the two groups matched in gender,age( ± 3)and region, and the match ratio was 1: 1. The research objects included were surveyed with questionnaire about influencing factors such as occupational exposure history,personality and psychology,lifestyle,diet and medical history. The data was analyzed by univariate and multivariate Logistic regression method. Results 1 220 cases were screened and 510 patients were diagnosed with nodular goiter,with detection rate of 41. 80% . There was significant difference in the detection rate of nodular goiter for people lived in different areas( χ2 = 5. 43,P < 0. 05). The detection rate of nodular goiter in town group was higher than that in mountain group( χ2 = 39. 54,P < 0. 007 ). The detection rate of nodular goiter in female was higher than that in male〔47. 91% (298 / 622)vs. 35. 45% (212 / 598),χ2 = 18. 94,P < 0. 01〕. The results of multivariate Logistic regression model analysis indicated that the independent influencing factors of nodular goiter included being female〔OR = 2. 33,95% CI(1. 59, 4. 12)〕,working in knitting textile〔 OR = 2. 31,95% CI(1. 89,4. 52)〕,die casting〔 OR = 2. 58,95% CI(1. 52, 4. 85)〕,long - term depression〔OR = 2. 11,95% CI(1. 28,3. 22)〕,consumption of marine products〔OR = 2. 35,95%CI(1. 04,4. 44)〕,X ray examination〔 OR = 3. 54,95% CI(2. 17,5. 88)〕,CT examination〔 OR = 2. 14,95% CI (1. 85,3. 98)〕(P < 0. 05). Conclusion The detection rate of nodular goiter in Xiangshan county is 41. 80% . Necessary occupational protection for special type of work,keeping a happy mood,rational diet,avoiding unnecessary X ray and CT examinations,and taking precautionary measures in advance for people in cities & towns and females are important manners to prevent nodular goiter.关键词
甲状腺肿,结节性/超声检查,多普勒,彩色/影响因素分析/病例对照研究Key words
Goiter,nodular/Ultrasonography,Doppler,color/Root cause analysis/Case - control studies分类
医药卫生引用本文复制引用
叶众,陈磊,陆昱养,郑广勇,陈子萌..浙江省象山县结节性甲状腺肿检出率及影响因素调查研究[J].中国全科医学,2016,19(35):4370-4374,5.基金项目
象山县科技局科技计划基金项目 （）
