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三阴性乳腺癌中P53和Ki-67的表达与临床病理特征的关系

潘如燕 曹源

中国社区医师2016,Vol.32Issue(33):136-137,2.
中国社区医师2016,Vol.32Issue(33):136-137,2.DOI:10.3969/j.issn.1007-614x.2016.33.84

三阴性乳腺癌中P53和Ki-67的表达与临床病理特征的关系

The expression of P53 and Ki-67 in three negative breast cancer and its relationship with clinical pathological characteristics

潘如燕 1曹源2

作者信息

  • 1. 222007江苏联合职业技术学院连云港中医药分院
  • 2. 222000连云港市疾病预防控制中心
  • 折叠

摘要

Abstract

Objective:To explore the expression of P53 and Ki-67 in three negative breast cancer and its relationship with clinical pathological characteristics.Methods:50 patients with three negative breast cancer were selected,and the expression of P53 and Ki-67 were detected.Results:In three negative breast cancer,P53 expression was correlated with histological grade(P<0.05),and no correlation with clinical stage and lymph node metastasis(P>0.05).The expression level of Ki-67 was correlated with clinical stage,histological grade and lymph node metastasis(P<0.05).Conclusion:Ki-67 can be used as an independent index to determine the prognostic effect of TNBC.

关键词

TNBC/P53/Ki-67/免疫组织化学

Key words

Three negative breast cancer/P53/Ki-67/Immuno histochemistry

引用本文复制引用

潘如燕,曹源..三阴性乳腺癌中P53和Ki-67的表达与临床病理特征的关系[J].中国社区医师,2016,32(33):136-137,2.

中国社区医师

1007-614X

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