中国药房2016，Vol.27Issue(33)：4735-4738,4.DOI:10.6039/j.issn.1001-0408.2016.33.43
参附益肾胶囊的质量标准研究
Study on Quality Standard of Shenfu Yishen Capsule
摘要
Abstract
OBJECTIVE:To establish the quality standard for Shenfu yishen capsule. METHODS:The microscopic characteris-tics of Gymnadenia conopsea were detected;TLC was adopted for the qualitative identification of Salvia miltiorrhiza,Rheum pal-matum,Glycyrrhiza uralensis,Rhodiola rosea and Cortex cinnamomi;HPLC was used for the content determination of astragalo-side:the column was Phenomenex Luna-C18 with mobile phase of acetonitrile-water(35∶65,V/V)at a flow rate of 1.0 ml/min,col-umn temerpature was 30 ℃. RESULTS:Microscopic identification features of G. conopsea were exclusive,TLC identification of S. miltiorrhiza,R. palmatum,G. uralensis,R. rosea and C. cinnamomi was well separated and specific;the linear range of astraga-loside was 0.832 8-4.164 0 µg(r=0.999 9);RSDs of precision,stability and reproducibility tests were no higher than 2.03%;re-covery was 95.02%-104.33%(RSD=3.80%,n=6). CONCLUSIONS:The standard can effectively control the quality of Shenfu yishen capsule.关键词
参附益肾胶囊/质量标准/薄层色谱法/高效液相色谱法/黄芪甲苷Key words
Shenfu yishen capsule/Quality standard/TLC/HPLC/Astragaloside A分类
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盛春帅,周鹃,李海霖..参附益肾胶囊的质量标准研究[J].中国药房,2016,27(33):4735-4738,4.
