中国药业2016，Vol.25Issue(20)：39-41,3.
CAF化疗方案、曲妥珠单抗配合情绪干预治疗胃癌临床疗效评价
CAF Regimen,Trastuzumab Combined with Emotional Intervention on Patients with HER2-Positive Gastric Cancer
宇晓蕾 1李斐 1刘嘉1
作者信息
- 1. 首都医科大学附属北京世纪坛医院，北京 100038
- 折叠
摘要
Abstract
Objective To observe the influence on the clinical efficacy of CAF regimen,trastuzumab combined with emotional intervention on patients with HER2-Positive Gastric Cancer. Methods 96 patients with HER-2 positive gastric cancer (≥75% ) from January 2014 to August 2015 in the hospital were selected and randomly divided into the observation group and the control group,48 cases in each group. The control group was treated with CAF regimen,on this basis,the observation group was given trastuzumab. Both groups were given emotional intervention for 18 weeks. The clinical efficacies of the two groups were observed;the level of the tumor marker and length of solid tumor were detected;the adverse reactions were recorded. Results The total effective rate of the observation group was 60. 42%,which was higher than 41. 67% of the control group( P < 0. 05). After treatment,the length of solid tumor in the obser-vation group was shorter than that in the control group( P < 0. 05),and the levels of the tumor marker CEA,CA199 and CA125 were lower than the control group( P < 0. 05). There was no significant difference in the adverse reactions between the two groups( P > 0. 05). Conclusion CAF regimen,trastuzumab combined with emotional intervention can achieve good clinical efficacy on patients with HER2-Positive Gastric Cancer by reducing the levels of tumor marker and with fewer adverse reactions,which is worthy of clinical promotion.关键词
人表皮生长因子受体2/胃癌/CAF化疗方案/曲妥珠单抗/情绪干预/临床疗效Key words
HER-2/gastric cancer/CAF regimen/trastuzumab/emotional intervention/clinical efficacy分类
医药卫生引用本文复制引用
宇晓蕾,李斐,刘嘉..CAF化疗方案、曲妥珠单抗配合情绪干预治疗胃癌临床疗效评价[J].中国药业,2016,25(20):39-41,3.
