中国药业2016，Vol.25Issue(21)：20-23,24,5.
低频超声联合抗菌药物治疗细菌生物被膜感染文献计量分析
Bibliometric Analysis of Low-Frequency Ultrasound Combined with Antimicrobial Agents in Treating Bacterial Biofilm Infection
摘要
Abstract
Objective To investigate the combination of low-frequency ultrasound combined with antimicrobial agents in treating bacteri-al biofilm infection in the databases since establishment to June 2016 based on a bibliometric approach, to provide reference in the an-ti-infection research. Methods PubMed, EMbase and CNKI were searched. The amount of year, corresponding authors, literature types, journal, content and cited frequency were statistically analyzed. The contents of the researches were discussed. Results A total of 194 papers were found and 58 papers were included in this study. The number of papers published showing an overall upward trend. Pitt WG was the corresponding author that published the most number of papers. The main publication type was basic research, accounting for more than 50%. The highest cited frequency of paper was 81 times. The maximum number of journal was Antimicrobial Agents and Chemotherapy. The contents of basic researches suggested that low frequency ultrasound and antimicrobial agent combination had synergy efficacy, but the mechanism was not clear and the synergistic effect in clinic needed further research. Conclusion The research of low-frequency ultrasound and antimicrobial agent combination against bacterial biofilm is in the stage of preliminary study and could be a promising method to treat biofilm infection.关键词
低频超声/生物被膜/抗菌药物Key words
low-frequency ultrasound/bacterial biofilm/antibacterial agents分类
医药卫生引用本文复制引用
刘旭,项荣武..低频超声联合抗菌药物治疗细菌生物被膜感染文献计量分析[J].中国药业,2016,25(21):20-23,24,5.基金项目
中国人民解放军总医院临床扶持基金，项目编号2015FC－TSYS－1042。 （）
