摘要
Abstract
Objective To explore the clinical efficacy of Shenqi Jiangtang Granules combined with acarbose in treating elderly patients with type 2 diabetes of Qi-Yin deficiency and its influence on serum inflammatory factors. Methods 120 cases of elderly patients with type 2 diabetes treated in the hospital were divided into two groups randomly,60 cases in each group. The control group was treated with acarbose,and the study group was treated with Shenqi Jiangtang Granules on the basis of the control group. 30 d was 1 course of treatment,and the two groups were treated for 4 courses continuously. The clinical efficacy and adverse reactions in the two groups were compared,and fasting plasma glucose (FPG),postprandial-2 h blood glucose (2 h PG),and changes of glycosylated hemoglobin (HbA1C) levels and interleukin -6 (IL-6),tumor necrosis factor alpha (TNF-α),high sensitive-C reactive protein (hs-CRP) levels were checked before and after treatment in the two groups. Results The total effective rate of the study group was 95. 00%,which was significantly higher than 73. 33% of the control group( P < 0. 05). After treatment,the levels of FPG,2 h PG,HbA1C, IL-6,TNF-α,and hs-CRP significantly decreased in the two groups( P < 0. 05),and the decreases in the study group were signif-icantly more than those of the control group( P < 0. 05). There was no significant difference in the incidence rate of adverse reactions between the two groups( P > 0. 05). Conclusion Shenqijiangtang granule combined with acarbose in treating elderly patients with type 2 diabetes has significant efficacy with high safety,which is worthy of clinical promotion.关键词
2型糖尿病/气阴两虚型/老年/阿卡波糖/参芪降糖颗粒/炎性因子Key words
type 2 diabetes/Qi-Yin Deficiency/agedness/acarbose/Shenqi Jiangtang Granules/inflammatory factors分类
医药卫生
