摘要
Abstract
Objective To observe and explore the clinical efficacy of Shenqi Jiangtang Granules combined with insulin in the treatment of type 2 diabetes. Methods A total of 240 cases of patients with type 2 diabetes from January 2014 to January 2015 in the hospital were randomly divided into two groups,120 cases in each group. All patients were treated by exercise and diet intervention at the same time,with the application of blood pressure control and blood lipid drug according to the actual condition. The control group was treated with the injection of recombinant human insulin,and the observation group was added with Shenqi Jiangtang Granules on the basis of the control group. After 3 months of continuous medication,the changes of fasting plasma glucose(FPG),postprandial 2 hour plasma glucose(2hPG),glycosylated hemoglobin(HbA1C),islet beta cell function(HOMA-β) were compared between the two groups,and the incidence rate of adverse reactions were recorded. Results After the treatment,the blood glucose parameters(FPG,2hPG,HbA1C)in the two groups were decreased,but the observation group decreased more significantly than the control group( P < 0. 05). Compared with before treatment,the control group had no significant change in HOMA-β,while the observation group was significantly improved in HOMA-β( P < 0. 05). The liver and renal function of the two groups were not abnormal,the adverse reactions were mild,and the inci-dence rates of the two groups had no statistically significant difference. Conclusion Shenqi Jiangtang Granules combined with insulin can effectively control the blood glucose level and improve the efficacy of the patients with type 2 diabetes,and protect the function of pancreatic islet beta cells,which is worthy of clinical promotion.关键词
参芪降糖颗粒/重组人胰岛素/2型糖尿病/临床疗效Key words
Shenqi Jiangtang Granules/recombinant human insulin/type 2 diabetes/clinical efficacy分类
医药卫生
