军事医学2016，Vol.40Issue(11)：923-926,4.DOI:10.7644/j.issn.1674-9960.2016.11.017
登革病毒DNA疫苗的研究进展
Research progress and prospect of dengue virus DNA vaccine
摘要
Abstract
Dengue virus ( DENV) infection has been considered a serious global health issue .Therefore, the development of a safe and effective vaccine is an urgent public health priority .Compared with live attenuated and inactive vaccines , DNA vaccination represents an attractive alternative to traditional vaccines , as it confers many advantages , such as easy development and production , cost-effectiveness , no risk for infection , stability for storage and shipping , and long-term persistence of immunogens .This review introduced the research progress in some DENV DNA vaccines in terms of construction strategies , inoculation methods , immunization strategies , immunologic adjuvants and immune effect .关键词
登革病毒/登革热/DNA疫苗Key words
dengue virus/dengue fever/DNA vaccine分类
医药卫生引用本文复制引用
赵琪,安静,陈辉..登革病毒DNA疫苗的研究进展[J].军事医学,2016,40(11):923-926,4.基金项目
首都医科大学七年制导师项目（7NZDS2015019）；国家自然科学基金资助项目 （）
