摘要
Abstract
Objective To evaluate whether erythrocyte sedimentation rate (ESR) could evaluate disease activity of patient with systemic lupus erythematosus (SLE) .Methods Totally 77 SLE patients From June 2012 to December 2012 were included in this study ,diagnosis of American Rheumatism Association requirements ,male 14 cases ,female 63 cases ,ESR ,complement (C3 ,C4) ,anti dsDNA antibody and other test items completed detection on the day of treatment ,and allocated patients into two subgroups accord‐ing to SLEDAI score ,active group (n=44 ,SLEDAI>4) and inactive group (n=33 ,SLEDAI=0-4) .The above indicators of two groups were compared ,the correlation between each index and the SLEDAI score was calculated .Results ESR was significantly in‐creased in active group than inactive group[21(10 ,37)mm/h vs .11(5 ,21)mm/h ,Z= -2 .787 ,P=0 .005] .On the ability to distin‐guish whether the activity of SLE ,there was no significant difference in between ESR and C3 ,C4 ,anti dsDNA antibody(P>0 .05) . Pearson correlation analysis showed that ESR was positively correlated with SLEDAI score (r=0 .293 ,P=0 .010) .Conclusion ESR can be considered as an useful marker for assessment of disease activity in patient with SLE .关键词
系统性红斑狼疮/红细胞沉降率/活动性Key words
systemic lupus erythematosus/erythrocyte sedimentation rate/activity
