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胰腺癌术后行早期肠内免疫营养支持促进机体胃肠功能、免疫功能恢复的临床研究

叶培军

中国现代医学杂志2016,Vol.26Issue(22):46-49,4.
中国现代医学杂志2016,Vol.26Issue(22):46-49,4.DOI:10.3969/j.issn.1005-8982.2016.22.010

胰腺癌术后行早期肠内免疫营养支持促进机体胃肠功能、免疫功能恢复的临床研究

Effect of postoperative early enteral immunonutrition on recovery of gastrointestinal function and immune function in patients with pancreatic cancer

叶培军1

作者信息

  • 1. 郑州大学附属肿瘤医院 重症医学科,河南 郑州 450008
  • 折叠

摘要

Abstract

Objective To analyze the effect of postoperative early enteral immunonutrition on gastrointestinal func-tion and immune function recovery in pancreatic cancer patients. Methods Sixty cases of pancreatic cancer patients undergoing surgery in our hospital between September 2008 and November 2013 were chosen as research subjects. According to different nutritional intervention the patients were randomized into observation group and control group. The patients in the control group received routine nutritional intervention, while the patients in the observation group received early enteral immunonutrition. Nutritional status, gastrointestinal function and immune function were com-pared between the two groups after intervention. Results Serum albumin, prealbumin and transferrin levels in the observation group were higher than those in the control group 1 week and 2 weeks after treatment ( < 0.05) The re-covery time of bowel sound, flatus, bowel movement and stomach retention time in the observation group were shorter than those in the control group ( < 0.05). IgG, IgA, IgM, CD3+, CD4+ and CD4+/CD8+values in the observe group were higher than those in the control group, while CD8+ value was lower than that in the control group ( < 0.05). The incidences of abdominal distension, diarrhea and constipation in the observation group were lower than those in the control group. Conclusions Early enteral immunonutrition after surgery in pancreatic cancer patients can effec-tively improve the nutritional status of patients, promote recovery of gastrointestinal function, improve the body's overall immune function, and has a positive significance.

关键词

胰腺癌/肠内免疫营养/胃肠功能/免疫功能

Key words

pancreatic cancer/enteral immunonutrition/gastrointestinal function/immune function

分类

医药卫生

引用本文复制引用

叶培军..胰腺癌术后行早期肠内免疫营养支持促进机体胃肠功能、免疫功能恢复的临床研究[J].中国现代医学杂志,2016,26(22):46-49,4.

中国现代医学杂志

OA北大核心CSTPCD

1005-8982

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