摘要
Abstract
Objective:To study the efficacy of high-intensity non-invasive ventilation in stable chronic obstructive pulmonary disease patients with type Ⅱ respiratory failure.Method:36 patients with chronic obstructive pulmonary exacerbation and type Ⅱ respiratory failure in our department from July 2013 to February 2016 were selected,after treatment,the disease was still stable with carbon dioxide retention.According to the random number table method,they were divided into the experimental group and control group,each of 18 cases.Two groups of patients were discharged from hospital at home to continue the use of noninvasive ventilation,the experimental group used the high-inspiratory pressure,the control group used the conventional inspiratory pressure,before and after treatment for 6 months,the FVC,FEV1,PaCO2,PaO2 and dyspnea scores in the two groups were compared.Result:After treatment,the two groups of PaCO2 and PaO2 compared with before treatment, the differences were statistically significant(P<0.05),and the PaO2,PaCO2 of the experimental group compared with control group,the differences were statistically significant(P<0.05),but the FEV1 and FVC of experimental group compared with before treatment and control group,the differences were not statistically significant(P>0.05).After treatment,between the dyspnea score of the two groups compared,there was no significant difference (P>0.05).Conclusion:To stable chronic obstructive pulmonary disease patinets with type Ⅱ respiratory failure home high-intensity non-invasive ventilation can better decrease carbon dioxide retention,but it can’t better improve lung function and exercise power.关键词
高压力/家庭无创通气/慢性阻塞性肺疾病/呼吸衰竭Key words
High-intensity/Family non-invasive ventilation/Chronic obstructive pulmonary disease/Respiratory failure
