中国医学创新2016，Vol.13Issue(33)：40-43,4.DOI:10.3969/j.issn.1674-4985.2016.33.012
不同时机使用卡前列素氨丁三醇对预防产后出血的效果比较
Comparison of the Effect of Different Timing of the Use of Carboprost Tromethamine Injection in the Prevention of Postpartum Hemorrhage
摘要
Abstract
Objective:To observe the effect of the use of Carboprost Tromethamine Injection in the prevention of postpartum hemorrhage.Method:2433 patients with postpartum bleeding tendency in our hospital from January 2014 to July 2016 in our hospital were retrospectively analyzed,according to the use time of Carboprost Tromethamine Injection,all patients were divided into observation group(n=805) and control group(n=1628).All parturient in postpartum were given compound sodium chloride 500 mL+20 U oxytocin by intravenous infusion,and the observation group received 250 μg Carboprost Tromethamine Injection by directly deltoid injection.If the control group had oxytocin hemostatic failure and bleeding more than 300 mL vaginal delivery,cesarean section hemorrhage more than 600 mL,the control group received 250 μg Carboprost Tromethamine Injection.According to the two groups of maternal follow-up blood loss to decide whether to repeat the use of Carboprost Tromethamine Injection or combined with other hemostatic methods.Comparison of two groups of maternal postpartum hemorrhage incidence,2 hours,24 hours of blood loss,needed to combine other hemostatic methods and adverse reactions.Result:The incidence of bleeding in the observation group was 3.7%,the incidence of bleeding in the control group was 3.9%,there was no significant difference between the two groups(P>0.05). The observation group postpartum vagina and uterus bleeding and 2 h and 24 h were significantly lower than those in the control group,the differences were statistically significant(P<0.05).The observation group with 2 cases of uterine bleeding balloon,the control group used uterine hemostatic balloon in 19 cases,the difference was statistically significant (P<0.05).The two groups had a small number of maternal adverse reactions,improved after symptomatic treatment.Conclusion:Carboprost Tromethamine Injection can be effectively and safe reduce postpartum 2 hours and 24 hours haemorrhage for parturient with bleeding tendency,reduce the combination of uterine bleeding balloon,reduce the cost of the patients,and it is safe and effective.关键词
卡前列素氨丁三醇/产后出血/不同时机/效果Key words
Carboprost Tromethamine Injection/Postpartum hemorrhage/Different timing/Effect引用本文复制引用
李艺平,汪东霞,王秀中..不同时机使用卡前列素氨丁三醇对预防产后出血的效果比较[J].中国医学创新,2016,13(33):40-43,4.基金项目
中山市科技计划项目 （）
