中国医学创新2016,Vol.13Issue(34):115-117,118,4.DOI:10.3969/j.issn.1674-4985.2016.34.034
鼠神经生长因子治疗四肢创伤性骨不连27例临床疗效观察
The Observation of the Rat Nerve Growth Factor in the Treatment of Traumatic Limbs Nonunion
刘平胜 1黄潮桐 2陈隆福 3刘宇涛 3刘淦良3
作者信息
- 1. 广东医科大学研究生学院 广东 湛江 524000
- 2. 广东省东莞宏元堂中医院
- 3. 广东医科大学附属厚街医院
- 折叠
摘要
Abstract
Objective:To explore the effect of nerve growth factor (NGF) in treatment of limbs fracture nonunion and promotion effect of healing.Method:The clinic data of 27 cases with nonunion of limbs fractures from March 2003 to March 2014 were analyzed retrospectively.The X-ray showed no obvious callus growth,they were given injection of mouse nerve growth factor (NGF) in the gap of limbs fracture broken end once a week,for 8 weeks,and regular X-ray observation of bone nonunion status once 2 weeks.Result:27 cases were followed up for 10 months to 10 years.The healing of fracture were 26 cases,1 case had no obvious callus growth,the effective rate was 96.3%.Conclusion:Local injection of rat nerve growth factor for the treatment of nonunion has better treatment effect with safe and effective,little trauma,fewer complications and it is a particularly noninvasive and painless method of conservative treatment for nonunion patients,but further research is still lacking.关键词
鼠神经生长因子/四肢骨骨折/骨不连/创伤性/治疗Key words
Rat nerve growth factor/Limbs fracture/Nonunion/Traumatic/Treatment引用本文复制引用
刘平胜,黄潮桐,陈隆福,刘宇涛,刘淦良..鼠神经生长因子治疗四肢创伤性骨不连27例临床疗效观察[J].中国医学创新,2016,13(34):115-117,118,4.