摘要
Abstract
OBJECTIVE:To investigate the occurrence characteristics of adverse drug reaction ( ADR ) /adverse drug events ( ADE ) in Chongqing Wansheng District Nantong General Hospital ( hereinafter referred to as “our hospital”) , so as to standardize the rational drug use in clinic .METHODS:326 cases of ADR/ADE reported from Apr.2014 to Sept.2015 were collected, analysis was conducted on patients'age, gender, suspected drug categories , route of administration, involved organs and (or) systems, classification and prognosis, allergy history, etc. RESULTS: Of the 326 cases, patients ≥61 years old were 110 cases ( 33.74%); ADR/ADE induced by anti-infectious drugs took the lead ( 206 cases , 63.91%) .The main route of administration induced ADR/ADE were intravenous infusion(303 cases, 92.94%), followed by oral administration(19 cases, 5.83%); drugs that induced ADR/ADE were mainly anti-infectious drugs , totally 206 cases ( 63.91%) .ADR/ADE involved organs and ( or ) systems mainly performed as skin and its accessories damage (269 cases, 48.64%), followed by systemic damage(85 cases, 15.37%).Totally 185 ADR/ADE cases(56.75%) involved a single organ or system.The general ADR/ADE reports took the lead(277 cases, 84.97%), followed by new and general ADR/ADE(33 cases, 10.12%).7 patients had allergic history(2.15%) and 208 patients without any allergic history (63.80%), with 111 patients'(37.05%) allergy were unknown .CONCLUSIONS: The supervision and propaganda of ADR/ADE should be strengthened , the relevant quality control standard for the rational use of drugs should be developed and implemented to reduce harm drugs by the clinic , so as to promote the rational drug use in clinic .关键词
药品不良反应/药品不良事件/合理用药Key words
Adverse drug reaction/Adverse drug events/Rational drug use分类
医药卫生
