动物营养学报2016，Vol.28Issue(12)：50-56,7.DOI:10.3969/j.issn.1006-267x.2016.12.008
抗菌肽抑制脂多糖诱导的炎症反应
Inhibitory Effects of Antimicrobial Peptides on Lipopolysaccharide-Induced Inflammation
摘要
Abstract
Antimicrobial peptides ( AMPs) are a kind of small molecular polypeptide which show the specific antibacterial mechanism to multiple drug⁃resistant strains. In addition, with anti⁃inflammatory activity, AMPs relieve inflammation by directly neutralizing lipopolysaccharide ( LPS) and inhibiting the release of biological inflammatory factors. Meanwhile, they also affect the acquired immunity through the chemotaxis of leukocytes and promoting the proliferation of the immune cells to adjust the host immune system and play a protective role. This essay summarized the mechanism of LPS induced inflammation and the AMPs to inhibit LPS induced in⁃flammation in recent years.关键词
抗菌肽/脂多糖/炎症因子/抑制炎症机理Key words
AMPs/LPS/inflammatory factors/mechanism of inhibiting inflammation分类
农业科技引用本文复制引用
杨颜铱,陈芸,高爽,刘旗,陈憧,姚淑华,邓俊良..抗菌肽抑制脂多糖诱导的炎症反应[J].动物营养学报,2016,28(12):50-56,7.基金项目
教育部“长江学者和创新团队发展计划”创新团队项目（IRTO848）；四川农业大学双支计划 （）
