口腔疾病防治2016，Vol.24Issue(12)：681-687,7.DOI:10.12016/j.issn.2096-1456.2016.12.001
年轻恒牙牙髓再生性治疗的研究进展
The research progress of regenerative endodontic treatment for immature permanent teeth
摘要
Abstract
The pulpal or periapical diseases of immature permanent teeth often lead to incomplete root develop⁃ment. It is a challenge for us to figure out how to ensure the continuous growth of the teeth and the formation of roots.There are many cases about pulp regeneration reported recently. With the regeneration and differentiation ability of stem cells, which exist in residual pulp tissue, periapical and periodontal tissues, the regeneration of new vital pulp tis⁃sue was induced under proper conditions, which is highly vascularized and rich in connective tissue, thus prompting continuous root growth and development, increasing root length, thickening root canal walls, and facilitating the coarcta⁃tion of the apical foramen. Besides, clinical and radiographic examinations shows successful results about the regenera⁃tive treatment, which is of milestone significance. The pulp regeneration treatment is designed to replace the pathologi⁃cal dental pulp tissue with new regenerated pulp tissue, based on biological tissue engineering process. This process in⁃cludes two key parts: one is pulp revascularization, regenerating new vital pulp tissue in the root canal to achieve the continuous root growth and development;the other is tissue engineering, new pulp dentin complex is regenerated by the stem cells under the induction of suitable biological active scaffolds and growth factors. This article reviews about the re⁃search progress and clinical characteristics of aforementioned two key parts.关键词
年轻恒牙/牙髓再生/牙髓再血管化/组织工程/生长因子Key words
Immature permanent tooth/Pulp regeneration/Pulp revascularization/Tissue engineering/Growth factor分类
医药卫生引用本文复制引用
宋光泰,靳秋晨..年轻恒牙牙髓再生性治疗的研究进展[J].口腔疾病防治,2016,24(12):681-687,7.基金项目
湖北省自然科学基金 （）
