摘要
Abstract
Objective To investigate the relationship between 25(OH)D3 and gestational metabolic syndrome (GMS).Methods From January 2015 to January 2016 one hundred women diagnosed with GMS were recruited in GMS group from the department of obstetrics and gynecology in Guangdong Maternal and Child Health Care Hospital group , and another 100 healthy pregnant women were selected in control group.Blood 25(OH)D and related metabolic parameters of the cases were detected to analyze their correlation .Results To compare age, gravidity, delivery times and HDL-C levels, the differences had no statistical significance between GMS group and the control group (t value was 0.508, 1.010, 1.179 and 1.026, respectively, all P>0.05).In the GMS group BMI, TC, TG, LDL-C, systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting plasma glucose (FPG), HbA1c and serum free fatty acid (FFA) levels were significantly higher than those in the control group (t value was 9.284, 5.572, 4.480, 3.192, 6.184, 4.317, 8.689, 9.360 and 3.070, respectively, all P<0.05).Levels of 25(OH) D3 in cases in the GMS group were significantly lower than those in the control group (t=16.856, P<0.05).Multi factor analysis with logistic regression showed that BMI in pregnancy and HbA 1c were positively correlated with GMS but 25(OH)D3 level was negatively correlated with GMS (OR value was 1.797, 133.8 and -161.9, respectively).Conclusion Deficiency of 25(OH)D3 is an independent risk factor for GMS .关键词
25羟维生素D/妊娠期代谢性疾病综合征/相关性/妊娠Key words
25 (OH) D3/gestation metabolic syndrome (GMS)/correlation/gestation分类
医药卫生
