实用心电学杂志2016，Vol.25Issue(6)：411-415,450,6.DOI:10.13308/j.issn.2095-9354.2016.06.007
肺静脉开口面积及左心房容积指数与房颤患者血栓栓塞风险的相关性研究
The correlation of pulmonary vein ostium area and left atrial volume index with the risk of thromboembolic events in patients with atrial fibrillation
摘要
Abstract
Objective To investigate the correlation of pulmonary vein ostium area and left atrial volume index(LAVI)with the risk of thromboembolic events in patients with atrial fibrillation(AF). Methods A total of 206 non-valvular AF patients were continuously included in our study.Accord-ing to CHADS2 and CHA2 DS2-VASc scores,those scoring zero,1 point and no less than 2 points were divided into low-risk,average-risk and high-risk groups,respectively.All the patients were classified into thrombosis group and non-thrombosis group based on the results by transesophageal echocardiography(TEE)and brain computed tomography(CT).By the technology of multi-slice spiral computed tomography(MSCT),the ostium areas of left superior pulmonary vein (LSPV),left inferior pulmonary vein (LIPV),right superior pulmonary vein(RSPV)and right inferior pulmonary vein(RIPV)were measured.By transthoracic Doppler echocardiography,the upper and lower diam-eter,anteroposterior diameter,and left and right diameters of left atrium were measured while LAVI was calculated.By Spearman rank correlation analysis,the correlation of pulmonary vein ostium are-a and LAVI with the scores of thromboembolism risk was investigated.The clinical value of each in-dex in predicting thromboembolism of non-valvular AF patients was compared via ROC curve.Re-sults (i)According to CHADS2 scores,there were 73 cases(35.4%)in low-risk group,82 (39.8%)in average-risk group and 51 (24.8%)in high-risk group while according to CHA2 DS2-VASc scores,there were 41 cases(1 9.9%),67 cases(32.5%)and 98 cases(47.6%)separately in the three groups.LAVI,area of LSPV ostium,area of LIPV ostium,area of RSPV ostium and the total area of pulmonary vein ostium were significantly correlated with both CHADS2 and CHA2 DS2-VASc scores.(ii)LAVI,area of LSPV ostium,area of LIPV ostium and the total area of pulmonary vein ostium had diagnostic value in predicting the risk of thromboembolic events among non-valvular AF patients.Conclusion LAVI measured by TEE and area of pulmonary vein ostium by MSCT were correlated with CHADS2 and CHA2 DS2-VASc scores.These indices have some predictive value for thromboembolism risk of non-valvular AF patients.关键词
非瓣膜性心房颤动/卒中/肺静脉开口面积/左心房容积指数/血栓危险分层Key words
non-valvular atrial fibrillation/stroke/pulmonary vein ostium area/left atrial volume index/risk stratification of thrombus分类
医药卫生引用本文复制引用
王文娟,常栋,董颖雪,尹晓盟,夏云龙,高连君,张树龙..肺静脉开口面积及左心房容积指数与房颤患者血栓栓塞风险的相关性研究[J].实用心电学杂志,2016,25(6):411-415,450,6.基金项目
辽宁省自然科学基金资助项目 （）
