临床神经外科杂志2016，Vol.13Issue(6)：415-418,423,5.DOI:10.3969/j.issn.1672-7770.2016.06.005
迷走神经刺激术治疗难治性癫痫(附25例报告)
Vagus nerve stimulation for intractable epilepsy( report of 25 cases)
摘要
Abstract
Objective To explore the curative effects of vagus nerve stimulation ( VNS ) on intractable epilepsy .Methods The clinical data of 25 patients with intractable epilepsy , who were treated by VNS in our center from November 2009 to July 2016, were analyzed retrospectively . Results The follow up from 4 months to7 years showed that of 25 patients, 6(24%) belonged in MCHugh grade Ⅰ, 12(48%) in gradeⅡ, 4(16%) in gradeⅢand 3(12%) in grades Ⅳ~Ⅴ. Conclusions VNS is a safe and effective method to treat the intractable epilepsy .VNS may make seizure frequency reduce over 50% in more than 60% patients with intractable epilepsy .The present results suggested that the curative effect is correlated with the stimulation parameter and duration.关键词
难治性癫痫/迷走神经刺激术/治疗效果Key words
intractable epilepsy/vagus nerve stimulation/curative effects分类
医药卫生引用本文复制引用
林久銮,孙朝晖,张冰清,王海祥,宋宪成,刘一鸥,丰倩,徐成伟,柏建军..迷走神经刺激术治疗难治性癫痫(附25例报告)[J].临床神经外科杂志,2016,13(6):415-418,423,5.基金项目
国家重点基础研究发展计划(973计划)(2012CB720704) （973计划）
清华大学自主项目(2015THJ01) （2015THJ01）
