生物医学工程研究2016，Vol.35Issue(4)：270-273,4.DOI:10.19529/j.cnki.1672-6278.2016.04.11
101例手术切除的结直肠癌组织介电特性的探讨
Research on the Dielectric Properties of Malignant and Normal Colorectal Tissues from 1 0 1 Cancer Surgeries
摘要
Abstract
To verify whether the open-ended coaxial line method is effective to detect the differences between malignant and nor-mal colorectal tissues in relative permittivity and conductivity,and make a judgement of the pathological type of colorectal cancer.With the open-ended coaxial line method,adjusting the frequency range from 170 to 500 MHz,101 freshly excised colorectal cancerous specimens,obtained from the operation room of Zhujiang hospital,were detected both the relative permittivity and conductivity on the carcinoma nidus and normal mucosa,respectively.Seven frequency points including 170.32,212.90,255.48,298.06,383.22, 468.38 MHz and 500.00 MHz were selected for statistical analysis.Each specimen would be conducted pathological examinations after surgery.The relative permittivity and conductivity of malignant colorectal tissues were significantly higher than those of normal ones(P<0.01).Compared with adenocarcinoma tissue,mucinous adenocarcinoma tissue had higher conductivity at the frequency points of 170.32,212.90,255.48,298.06 and 383.22 MHz (P<0.05).And there showed no significances among the dielectric properties of three differentiated degrees,namely well-differentiated,middle-differentiated and poor-differentiated(P>0.05 ).The open-ended coaxial line method can not only identify the differences between malignant and normal colorectal tissues,but also decide which pathological type the colorectal cancer belongs to.关键词
开端同轴线/相对介电常数/电导率/结直肠癌/病理类型Key words
Open-ended coaxial line/Relative permittivity/Conductivity/Colorectal cancer/Pathological type分类
医药卫生引用本文复制引用
王卫卫,厉周,林世明,韩帅,陈妙良,段松,辛学刚,蔡寨..101例手术切除的结直肠癌组织介电特性的探讨[J].生物医学工程研究,2016,35(4):270-273,4.基金项目
国家自然科学基金资助项目（61172034，61528102）；广东自然科学基金资助项目（2015A030313234）；广州市科技计划（2014J4100160）；南方医科大学科技开发计划项目（c1033046）。 （）
