上海针灸杂志2016，Vol.35Issue(12)：1459-1461,3.DOI:10.13460/j.issn.1005-0957.2016.12.1459
隔物温和灸对膝骨关节炎患者血清IL-1及TNF-含量的影响
The Effect of Indirect Gentle Moxibustion on Serum IL-1 and TNF- Contents in Patients with Knee Osteoarthritis
摘要
Abstract
Objective To investigate the effect of indirect gentle moxibustion on serum IL-1 and TNF-contents in patients with knee osteoarthritis and explore the mechanism of its action. Method A randomized controlled trial was conducted according to the patient's condition. Besides acupuncture as basic treatment, the treatment group received indirect gentle moxibustion and the control group, thermotherapy plus cupping. Pre-treatment and post-treatment serum IL-1 and TNF-contents and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores were analyzed in the patients and compared between the two groups. Result There were statistically significant pre-/post-treatment differences in serum IL-1 and TNF- contents and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score in the two groups (P<0.05). After treatment, serum IL-1 and TNF-contents and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score were lower in the treatment group than in the control group. Conclusion Indirect gentle moxibustion can effectively decrease serum IL-1 and TNF-contents in patients with knee osteoarthritis. That provides a certain molecular cytobiological and bio tissue engineering basis for the mechanism of its action in reducing inflammatory stimulation.关键词
针刺/骨关节炎,膝关节/白细胞介素1/肿瘤坏死因子/艾条灸/药饼灸疗法/电针Key words
Acupuncture/Osteoarthritis, knee/IL-1/TNF-/Moxa stick moxibustion/Indirect moxibustion/Medicinal cake-partitioned moxibustion/Electroacupuncture分类
医药卫生引用本文复制引用
李秀彬,李正祥,王立新..隔物温和灸对膝骨关节炎患者血清IL-1及TNF-含量的影响[J].上海针灸杂志,2016,35(12):1459-1461,3.基金项目
温岭市科技项目(2014C31BC0011) （2014C31BC0011）
