现代检验医学杂志2016,Vol.31Issue(6):121-123,3.DOI:10.3969/j.issn.1671-7414.2016.06.035
革兰氏阴性细菌感染患者血清内毒素检测临床探讨
Detection of Serum Endotoxin in Patients with Gram Negative Bacterial Infection
摘要
Abstract
Objective To investigate the clinical application of bacterial ndotoxin (ET)in the patients with gram-negative bac-terial infections.Methods 200 ases sent for bacterial culture for the detection of patients.At the same time,blood samples were taken by kinetic turbidimetric technique with limulus reagent on the line ET levels were measured.Results Specimens in 112 cases of ET level greater than 0.030 EU/ml.Bacteria was detected in 39 cases of patients were culture and gram neg-ative bacteria (G-)in 24 cases,ET test results 0.264±0.109 EU/ml,were greater than 0.115 EU/ml;gram positive bacte-ria (G+)in 15 cases,ET results 0.023±0.025 EU/ml,two group comparison,the difference had statistical significance (t=28.23,P<0.05).Conclusion Blood ET increase is correlated with G- bacteria infection,first with the detection of ET have to on patients with G- bacteria infection in early diagnosis and treatment and provide a theoretical basis.关键词
细菌内毒素/革兰氏阴性菌/细菌培养/感染性疾病Key words
bacterial endotoxin/gram negative bacteria/bacterial culture/infectious disease分类
医药卫生引用本文复制引用
袁平宗,汤雪彪,王小龙,李传达..革兰氏阴性细菌感染患者血清内毒素检测临床探讨[J].现代检验医学杂志,2016,31(6):121-123,3.基金项目
国际医学研究基金(亚洲区)临床微生物学专项基金项目(项目编号CNSC-J2011-A3300)。 ()