现代检验医学杂志2016，Vol.31Issue(6)：147-149,3.DOI:10.3969/j.issn.1671-7414.2016.06.044
中性粒细胞淋巴细胞比率在衡量肥胖病人炎症状态的初步探讨
Preliminary Study on Neutrophil-Lymphocyte Ratio as an Indicator of Inflammatory State in Obese Patients
顾进 1侯思南 1许海英2
作者信息
- 1. 连云港市中医院检验科，江苏连云港 222004
- 2. 连云港市中医院体检中心，江苏连云港 222004
- 折叠
摘要
Abstract
Objective To investigate the usage of the neutrophil-lymphocyte ratio (NLR)as an inflammatory marker in obese patients with and without metabolic syndrome(MetS).Methods Individuals whose BMI was >30 and 25kg/m2 were ac-cepted as obese and overweight according to WHO recommendations.253 subjects were selected according to degree of obe-sity and status of Mets and assigned groups as obese overweight and control group respectively.Metabolic and inflammatory markers were compared between groups and correlation analysis was performed.Results Leukocyte count and CRP were significantly different (P<0.001)between groups,both lymphocyte and neutrophil counts were significantly increased with increased degree of obesity (P<0.05),but NLR was not different between body mass index (BMI)groups (P=0.228). Leukocyte,neutrophil,and lymphocyte counts and CRP level showed a significant correlation with BMI (P<0.001),where-as NLR was not correlated with BMI (P=0.667).Conclusion NLR would not be a good indicator of inflammation while leukocyte count and CRP are more useful biomarkers to indicate inflammation in obese patients with and without MetS.关键词
中性粒细胞淋巴细胞比率/肥胖/炎症Key words
neutrophil-lymphocyte ratio/obesity/inflammation分类
医药卫生引用本文复制引用
顾进,侯思南,许海英..中性粒细胞淋巴细胞比率在衡量肥胖病人炎症状态的初步探讨[J].现代检验医学杂志,2016,31(6):147-149,3.
