摘要
Abstract
Objective To investigate the clinical effect of serum IgE antibody in the early diagnosis and treatment of asthmatic children. Methods Two hundreds and thirty-five asthmatic children aged 0-14 years old(asthma group) and 261 healthy children (control group) in our hospital from July 2014 to June 2016 were selected as the research subjects and 14 items of allergen IgE in these two groups were simultaneously detected,including 7 items of ingestant(egg,milk,sea fish,seafood,beef/mutton,fruit and nut food) and 7 items of inhalation(total IgE,dust mite,house dust,tree pollen,weed pollen,mold and animal dander). Results In 14 items of allergen IgE test results,the positive rate of the asthma group was generally higher than that of the control group,the difference was statistically significant(89.36%vs. 23.37%,P<0.05);The detection results in the groups of 0-3 years old,>3-6 years old and>6-14 years old and total detection results showed that the positive rate of ingestant and inhala tion in the asthma group was significantly higher than that in the control group,the difference was statistically significant(P<0.05);the positive kinds number in the 2,3,>4 kinds subgroups of the asthma group was significantly higher than that in the control group,the difference was statistically significant(P<0.05). Conclusion The positive rate of allergen IgE in asthmatic children is higher,which is mainly combined allergy with more than 2 kinds of item,the allergens are mainly ingestants in less than 3-14 years old and inhalations in more than 3 years old. Detecting serum specific IgE has an important guiding significance for the di-agnosis and treatment of child asthma.关键词
哮喘/变应原/过敏反应/儿童Key words
Asthma/Allergens/Anaphylaxis/Child
