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维生素D与川崎病的关系及作用机制研究进展

杨雪(综述) 董湘玉(审校)

中国当代儿科杂志2016,Vol.18Issue(12):1319-1323,5.
中国当代儿科杂志2016,Vol.18Issue(12):1319-1323,5.DOI:10.7499/j.issn.1008-8830.2016.12.024

维生素D与川崎病的关系及作用机制研究进展

Research advances in association between vitamin D and Kawasaki disease and related mechanisms of action

杨雪(综述) 1董湘玉(审校)1

作者信息

  • 1. 兰州大学第二医院儿科,甘肃兰州 730030
  • 折叠

摘要

Abstract

Vitamin D is an important steroid hormone, which has a wide biological effect and is the protective factor against cardiovascular disease and other diseases. At present, the etiology and pathogenesis of Kawasaki disease (KD) remain unknown, but recent studies have shown that vitamin D insufifciency or deifciency is associated with KD. Vitamin D insufifciency or deifciency may affect KD via its inlfuence on inlfammatory response, adipokine, endothelial function, platelet function, and DNA methylation and increase the risk of coronary artery lesions. This article reviews the research advances in the association between vitamin D and KD and possible mechanisms of action.

关键词

维生素D/川崎病/炎症反应

Key words

Vitamin D/Kawasaki disease/Inlfammatory response

引用本文复制引用

杨雪(综述),董湘玉(审校)..维生素D与川崎病的关系及作用机制研究进展[J].中国当代儿科杂志,2016,18(12):1319-1323,5.

中国当代儿科杂志

OA北大核心CSCDCSTPCD

1008-8830

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