COPD患者Th17细胞和 Treg细胞介导的免疫应答变化及免疫失衡与肺功能的关系研究OA北大核心CSCDCSTPCD
Relationship of immune response and immune imbalance mediated by Th17 cells and Treg cells with pulmonary function in COPD patients
目的：：探讨慢性阻塞性肺疾病( COPD)患者外周血Th17细胞和调节性T细胞( Treg)及其介导的免疫应答变化与患者肺功能的关系。方法：选取本院呼吸内科收治的90例COPD患者( COPD组)和同期年龄、性别基本匹配的45例健康体检对象作为对照组,并根据COPD病情进行亚组分析,分别测定各组研究对象肺功能指标、Th17细胞、Treg细胞及血清炎症因子水平。结果：在COPD患者间,随着病情加重,FEV1%、FVC%、FEV1/FVC比值中度CO…查看全部>>
Objective:To investigate the relationship of the immune response and immune imbalance mediated by Th17 cells and Treg cells with pulmonary function in chronic obstructive pulmonary disease ( COPD) patients. Methods:90 COPD patients and 45 healthy volunteers with matched age and sex were selected. The COPD patients were divided into 2 groups according to the patient's condition. 45 healthy volunteers were collected as the control group. The lung function, Th1…查看全部>>
门翔;尚喜雨
河南省南阳市中心医院呼吸内科一病区，南阳 473000河南省南阳市中心医院呼吸内科一病区，南阳 473000
医药卫生
慢性阻塞性肺疾病Th17细胞调节性T细胞免疫应答肺功能
Chronic obstructive pulmonary diseaseTh17 cellsRegulatory T cellsImmune responsePulmonary function
《中国免疫学杂志》 2016 (12)
1826-1829,4
河南省南阳医学高等专科学校基础部,南阳473000。
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