中国医学创新2016，Vol.13Issue(31)：13-16,4.DOI:10.3969/j.issn.1674-4985.2016.31.004
原发性肝癌患者血浆溶血磷脂酸的临床意义
Significance of Plasma Lysophosphatidic Acid Detection in patients with Primary Liver Cancer
摘要
Abstract
Objective:To observe the levels of plasma lysophosphatidic acid(LPA) in patients with primary liver cancer,and to evaluate its clinical potential of diagnosis.Method:Plasma LPA and serum AFP levels were measured in 43 patients with primary liver cancer,10 patients with benign primary liver cancer tumor,and 10 patients healthy donors.Result:Plasma LPA concentration in primary liver cancerpatients (3.94±0.60)µmol/L was significantly higher than patients with benign lesions of(2.68±0.36)µmol/L and control group of (2.42±0.35)µmol/L (P<0.05).Higher plasma LPA level showed a significant correlation with invasion and <br> portal vein tumor thrombus (PVTT) of primary liver cancer.Conclusion:Plasma LPA level may be a potential indicator of the diagnosis and prognosis of primary liver cancer.关键词
原发性肝癌/溶血磷脂酸/甲胎蛋白/诊断/预后Key words
Primary liver cancer/Lysophosphatidic acid/AFP/Diagnosis/Prognosis引用本文复制引用
解长佶,胡超,曹凯,张宇晴..原发性肝癌患者血浆溶血磷脂酸的临床意义[J].中国医学创新,2016,13(31):13-16,4.基金项目
江西省卫生计生委科技计划项目 （）
