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婴幼儿重症肺炎血PCT及乳酸监测的临床意义

张莉娜 万俊

中国医学创新2016,Vol.13Issue(31):21-23,24,4.
中国医学创新2016,Vol.13Issue(31):21-23,24,4.DOI:10.3969/j.issn.1674-4985.2016.31.006

婴幼儿重症肺炎血PCT及乳酸监测的临床意义

The Clinical Significance of Dynamic Monitoring Blood Procalcitonin and Lactic Acid in Infants and Young Children with Serious Pneumonia

张莉娜 1万俊1

作者信息

  • 1. 东南大学医学院附属江阴市人民医院 江苏 江阴214400
  • 折叠

摘要

Abstract

Objective:To analyze the clinical significance of dynamic monitoring blood PCT(procalcitonin) and lactic acid in infants and young children with serious pneumonia.Method:A total of 60 children with severe pneumonia were enrolled in the study,they were divided into bacterial pneumonia group with 38 cases and nonbacterial pneumonia group with 22 cases.And 30 healthy children were selected as control group.The value of PCT in children with pneumonia were detected before and after treatment. According to the prognosis of patients with severe pneumonia were divided into effective group and ineffective group,the arterial blood lactate,12 and 24 h lactate clearance rate of two groups were analyzed and compared.Result:Initial PCT level of bacterial pneumonia group was significantly higher than that of nonbacterial pneumonia and cotrol group,the differences were statistically significant(P<0.05).After 3 d treatment, the blood PCT value of bacterial pneumonia group was significantly decreased compared with before treatment, the difference was statistically significant(P<0.05).The arterial blood lactic acid value of bacterial pneumonia group and non bacterial pneumonia group were significantly higher than that in control group,the differences were statistically significant(P<0.05).There was no significant difference in the initial lactic acid level between the effective group and the ineffective group(P>0.05),but the 12 and 24 hours lactate clearance rates in effective group were significantly higher than ineffective group,the differences were statistically significant(P<0.05).Conclusion:The dynamic monitoring levels of blood PCT and lactic acid in infants and young children with serious pneumonia are the favorable indicators for differential diagnosing,condition judgment,evaluation of therapeutic efficiency and prognosis.

关键词

婴幼儿/重症肺炎/降钙素原/乳酸

Key words

Infants and young children/Serious pneumonia/Procalcitonin/Lactic acid

引用本文复制引用

张莉娜,万俊..婴幼儿重症肺炎血PCT及乳酸监测的临床意义[J].中国医学创新,2016,13(31):21-23,24,4.

中国医学创新

1674-4985

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