中国医学创新2016，Vol.13Issue(32)：106-108,3.DOI:10.3969/j.issn.1674-4985.2016.32.030
急诊无创正压通气联合小剂量肾上腺素治疗重症支气管哮喘合并呼吸衰竭的临床效果研究
Clinical Efficacy of Non Invasive Positive Pressure Ventilation Combined with Small Dose of Epinephrine in the Treatment of Severe Bronchial Asthma Complicated with Respiratory Failure
摘要
Abstract
Objective:To study the clinical efficacy of non invasive positive pressure ventilation combined with small dose of Epinephrine in the treatment of severe bronchial asthma complicated with respiratory failure. Method:From June 2012 to May 2016 70 cases of severe bronchial asthma with respiratory failure patients, two groups were given basic treatment,oxygen,asthma,anti-inflammatory hormone,treatment and routine emergency antispasmodic expectorant,the control group received noninvasive positive pressure ventilation treatment,on the basis of above the observation group treated with small doses of Epinephrine.Result:The changes of RR and HR in two groups after 72 h treatment were significant (P<0.05),there were statistically significant differences between two groups of RR and HR after 72 h treatment(P<0.05).The content of PaO2 and pH value in two groups were significantly increased after 72 h treatment,the content of IL-17,ECP,MPO,MDC in two groups reduced significantly after 72 h treatment(P<0.05).The content of PaO2 of the observation group was significantly higher than that of the control group after 72 h treatment(P<0.05),The content of PaCO2 of the observation group was significantly lower than that of the control group after 72 h treatment(P<0.05).There were statistically significant differences between two groups of efficiency of treatment and invasive positive pressure ventilation after 72 h treatment(P<0.05).Conclusion:Non invasive positive pressure ventilation combined with small dose of Epinephrine in the treatment of severe bronchial asthma with respiratory failure can significantly improve the blood gas and inflammatory factors,and effectively improve the clinical efficacy.关键词
无创正压通气/急性重症哮喘/小剂量肾上腺素/呼吸衰竭Key words
Non invasive positive pressure ventilation/Acute severe asthma/Low dose Epinephrine/Respiratory failure引用本文复制引用
黄运忠,曹德,张小凤..急诊无创正压通气联合小剂量肾上腺素治疗重症支气管哮喘合并呼吸衰竭的临床效果研究[J].中国医学创新,2016,13(32):106-108,3.基金项目
广东省中医药局项目 （）
