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中药饮片超微粉碎实现剂型改革的初步试验

丁圣清 郁省 王冬东 施菲 焦志铁

中国药业2016,Vol.25Issue(23):38-42,5.
中国药业2016,Vol.25Issue(23):38-42,5.

中药饮片超微粉碎实现剂型改革的初步试验

Preliminary Experiment on Improving the Formulation of Superfine Pulverization of Traditional Chinese Medicine

丁圣清 1郁省 2王冬东 3施菲 3焦志铁1

作者信息

  • 1. 江苏省扬州市第一人民医院,江苏 扬州 225009
  • 2. 江苏省扬州市妇幼保健院,江苏 扬州 225002
  • 3. 扬州大学,江苏 扬州 225001
  • 折叠

摘要

Abstract

Objective To investigate the changes of the properties of five Chinese herbal medicines, Epimedium, Hedtotis diffusa, Radix Astragali, Magnolia officinalis and Scutellaria barbata after ultrafine pulverization, to state the necessitt of application of ultrafine com-minution in traditional Chinese medicine. Methods Herbs such as Epimedium, Hedtotis diffusa, Radix Astragali, Magnolia officinalis and Scutellaria barbata were processed bt ultra-fine crushing and drt granulation. The bulk densitt, microscopic characteristics, particle size, the index component dissolution, etc. were investigated. Results After ultrafine pulverization of Chinese herbal medicines, the particle size reached nanometer scale, the cell wall was broken, the tield of extract was high, and the dissolution rate of the index components was fast. Conclusion The ultrafine powder granulation of Chinese herbal medicine is a scientific reform of the dosage form of traditional Chinese medicine decoction, which can improve the qualitt of medicine and save manpower bt using automatic dispensing ststem. It is of clinical significance to further improve the accurate quantification of traditional Chinese medicine decoction.

关键词

超微粉碎/质量评价/中药饮片/自动化调配/临床应用

Key words

ultrafine comminution/qualitt evaluation/traditional Chinese medicine decoction/automatic dispensing/clinical application

分类

医药卫生

引用本文复制引用

丁圣清,郁省,王冬东,施菲,焦志铁..中药饮片超微粉碎实现剂型改革的初步试验[J].中国药业,2016,25(23):38-42,5.

中国药业

OACSTPCD

1006-4931

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