分析测试学报2016，Vol.35Issue(11)：1440-1444,5.DOI:10.3969/j.issn.1004-4957.2016.11.012
高效液相色谱-串联质谱法同时测定农田土壤中的六溴环十二烷和四溴双酚A
Determination of Hexabromocyclododecanes and Tetrabromobisphenol A in Farmland Soils by High Performance Liquid Chromatography-Tandem Mass Spectrometry
摘要
Abstract
A high performance liquid chromatography-tandem mass spectrometric method(HPLC-MS/MS) was developed for the simultaneous determination of hexabromocyclododecanes(HBCDs) and tetrabromobisphenol A(TBBPA) in farmland soils.Samples were extracted by accelerated solvent extraction(ASE) and purified with Sep-pak C18 solid phase extraction(SPE) cartridges.The targeted compounds were separated on an X Bridge C18(150 mm × 2.1 mm × 3.5 μm) using methanol-water as mobile phases,and then analyzed by HPLC-MS/MS in multiple reaction monitoring(MRM) mode with negtive electrospray ionization.The target compounds had good linear relationships(r≥ 0.998) in the range of 0.50-200.0 μg/L.The limits of detection(S/N ≥ 3) were in the range of 1.80-10.0 ng/kg,and the average recoveries at spiked levels of 1.0- 40.0 μg/kg ranged from 73.8% to 106.9%with RSDs of 5.8%-11.2%.The method was successfully applied in the detection of HBCDs and TBBPA residues in practical farmland soils.关键词
加速溶剂萃取/高效液相色谱-串联质谱(HPLC-MS/MS)/农田土壤/六溴环十二烷(HBCDs)/四溴双酚AKey words
accelerated solvent extraction(ASE)/high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)/farmland soil分类
化学化工引用本文复制引用
王晓春,陶静,李铁纯..高效液相色谱-串联质谱法同时测定农田土壤中的六溴环十二烷和四溴双酚A[J].分析测试学报,2016,35(11):1440-1444,5.基金项目
国家自然科学基金资助项目(41430641,41140032) （41430641,41140032）
中国地质局地质调查工作项目(1212351211006) （1212351211006）
