摘要
Abstract
Objective To investigate the influence of epidural anesthesia on reducing the postoperative cognitive function of elderly orthopedic patients and provide a scientific method choosing anesthesia.Methods 200 elderly bone fracture patients undertaking open reduction and internal fixation at the department of orthopedics of our hospital from January,2013 to June,2015 were randomly selected and divided into an observation group and a control group by random number table,100 for each group.The intra-operative arterial pressure and heart rate were compared between these two groups.Mini-mental status examination scale (MMSE) was used to evaluate the patients' cognitive function.Results The anesthesia time,bleeding volume,infusion volume,mean arterial pressure,and heart rate were (191.5±30.6) min,(345.7±58.1) ml,(2088.6±160.5) ml,(11.9±0.9) kPa,and (84.1±5.7)beats/min in the observation group,and were (89.5±27.6)min,(40.2±57.5)ml,(100.5±158.9) ml,(1.8±0.9) kPa,and (3.6±5.8) in the control group,with no statistical differences.Before and 6,12,and 72 h after anesthesia,the cognitive MMSE scores were (29.2±1.1) and (9.3±0.9),(26.2 ± 0.5) and (6.3 ± 0.5),(25.4 ± 0.5) and (5.5 ± 0.6),and (29.3 ± 0.8) and (9.1 ± 0.8) in the observation group and the control group,respectively,with no statistical differences (P ＞ 0.05);24 h after anesthesia,the cognitive MMSE score was (29.4 ± 0.7) in the observation group and was (27.0 ± 0.9) in the control group,with a statistical difference (P ＜ 0.05).Conclusion Epidural anesthesia has less effect on cognitive function in elderly orthopedic patients,so it is worth being learnt.关键词
认知功能/全身麻醉/硬膜外麻醉Key words
Cognitive function/General anesthesia/Epidural anesthesia
