河北工业科技2016，Vol.33Issue(6)：479-483,5.DOI:10.7535/hbgykj.2016yx06007
青风藤配方颗粒的制备及与传统汤剂的比较
Preparation of formula granules of Caulis Sinomenii and comparison between formula granules and traditional decoction of Caulis Sinomenii
摘要
Abstract
In order to study the preparation of Caulis Sinomenii formula granules and conduct qualitative and quantitative comparison of formula granules and traditional decoction, by adopting dry granulating and taking the ratio of extraction and the contents of sinomenine as indexes, the paper uses the orthogonal test method to prepare Caulis Sinomenii formula granules.TLC is used for qualitative comparison, and HPLC is used for quantitative comparison with Sinomenine as reference substance.The results show that the best preparation of formula granules is adding 18 times water(the first added amount is 10 times, and the second added amount is 8 times) and extracting 2 times for 1.0 hour respectively.The sinomenine contents of 5 group of formula granules are 1.56%, 1.58%, 1.31%, 1.20% and 1.78%.The sinomenine contents of the 5 group of trdaditional decoction of Caulis Sinomenii are 0.94%, 0.96%, 0.85%, 0.82% and 1.02%.The result shows that the chemical constituents of the formula granules and the traditional decoction are similar, but the contents of sinomenine are different.关键词
化学分析/青风藤/配方颗粒/传统汤剂/青藤碱Key words
chemical analysis/Caulis Sinomenii/ formula granules/traditional decoction/Sinomenine分类
医药卫生引用本文复制引用
赵帆帆,王娇娇,李丽丽,李建晨,哈婧..青风藤配方颗粒的制备及与传统汤剂的比较[J].河北工业科技,2016,33(6):479-483,5.基金项目
河北省食品药品监督管理局科技项目(ZD2015025) （ZD2015025）
