哈尔滨商业大学学报(自然科学版)2016,Vol.32Issue(6):659-662,4.
CyclinB1与肿瘤细胞周期调控
CyclinB1 and cell cycle regulation
摘要
Abstract
Cell cycle is the most important process of cellular activities , whose key is the start of the G1 and G2 phase.CyclinB1 is the key protein that regulates G 2 phase, which is critical to the regulation of cell cycle .This paper reviewed the structure and function of CyclinB 1 andthe regulation of its effector molecules on cell cycle , especially the regulation of G 2/M phase .And also reviewed the connection between CyclinB 1 mediated abnormal cellcycle reg-ulation and its expression in tumour tissues .And provided a new target and direction for tumor therapy .关键词
CyclinB1/肿瘤/细胞周期调控Key words
CyclinB1/tumour/regulation of cell cycle分类
医药卫生引用本文复制引用
贾未玲,于淼..CyclinB1与肿瘤细胞周期调控[J].哈尔滨商业大学学报(自然科学版),2016,32(6):659-662,4.基金项目
国家自然科学基金资助项目(81274067);中国博士后科学基金(2015M581467);黑龙江省自然科学基金资助项目(D201138);黑龙江省博士后科学基金(LBH-Z15107);黑龙江省教育厅科技重点项目(12511z011);黑龙江省高等学校科技创新团队项目(2014TD009);哈尔滨市青年科技创新人才专项资金(2013RFQXJ150)黑龙江省青年创新人才培养计划 ()