摘要
Abstract
Objective:Using two-dimensional speckle tracking imaging(2DSTI)and real-time three-di-mensional echocardiography(RT-3DE)to evaluate the left ventricular systolic function and synchrony in pa-tients with uremic myocardiopathy(UM).Methods:Thirty-three cases of UM patients and 35 normal sub-jects were enrolled in this study.The left ventricular end-diastolic internal diameter(LVEDd ),left ventric-ular end-systolic internal diameter (LVESd),interventr icular septum diameter(IVSd),left ventricular posterior wall diameter(LVPWd)and M-mode ejection fraction (M-EF)were obtained on M-Teichholz method.The two-dimensional dynamic gray-scale images of left ventricular shoRT-axis views of the basal, middle and apical plane were acquired.Peak systolic circumferential strain(C.Strain)and Peak systolic circumferential strain rate(C.Strain .Rate)of 16 segments (except apex cordis)were analysed by Qlab software.RT-3DE was wsed to obtain the left ventricular full-volume images and used Qlab 9.0 software to analyze datas,such as the end diastolic volume(LVEDV),end systolic volume(LVESV)and ejection fraction(EF3d )of left ventricule,in addition the time to minimal systolic volume (Tmsv)of 16,12,6-seg-mental standard deviation(Tmsv 16,12,6-SD)was calculated.The maximal difference of correspongding segments(Tmsv 16,12,6-Dif)were also derived from Qlab software,The above parameters as a percentage of the cardiac cycle with different heart rates between patients were also calculated from the Qlab software, which were Tmsv 16,12,6-SD /R-R(%)and Tmsv 16,12,6-Dif/R-R(%),rspectively.Results:The in-dices of LVEDd,IVSd,LVPWd and LVESV were significantly higher while EF3d were significantly lower in the UMgroup than those of control group(P <0.05);both C.Strain and C.Strain.rates of UM group were significantly lower than those of control group(P <0.01).As to Tmsv 16-SD,Tmsv 12-SD,Tmsv 6-SD, Tmsv 16-Dif,Tmsv 12-Dif and Tmsv 6-Dif,all parameters in UM group were higher than those of control group (P <0.01).Conclusion:2DSTI and RT-3DE can be used to evaluate the left ventricular systolic func-tion and synchrony in patients with uremic myocardiopathy more accurately and noninvasively.关键词
二维斑点追踪技术/实时三维超声心动图/尿毒症性心肌病/左心室收缩功能/收缩同步性Key words
two-dimensional speckle tracking imaging/real-time three-dimensional echocardiography/uremic myocardiopathy/left ventricular systolic function/left ventricular systolic synchrony分类
医药卫生
